Gestational trophoblastic disease: our patients deserve better case detection and follow up.
نویسنده
چکیده
The World Health Organisation’s (WHO) classification of gestational trophoblastic disease includes complete, partial, invasive and metastatic hydatidiform mole, exaggerated placental site nodule or plaque and two malignant tumoursplacental site trophoblastic tumour and choriocarcinoma [1]. The incidence of gestational trophoblastic disease (GTD) in Sri Lanka according to a hospital based study is 1 in 213 pregnancies [2] as compared to 1 in 2000 pregnancies in the USA [3]. Complete moles (CMs) are more common in Asian women [4]. The incidence of partial moles (PMs) is similar to that of CMs. PMs tend to be less often recognised clinically or pathologically, since their appearances are more subtle and easily misinterpreted as a spontaneous abortion by clinicians or as ‘products of conception’ by pathologists. Ideally, all tissue from a spontaneous abortion in the first trimester should be sent for histological examination for evidence of GTD.
منابع مشابه
Gestational trophoblastic disease: experience at a tertiary care hospital of Sindh.
OBJECTIVE To determine the frequency, clinical presentation and management outcomes of Gestational Trophoblastic Disease (GTD). STUDY DESIGN Descriptive case series. PLACE AND DURATION Department of Gynaecology and Obstetrics, Liaquat University of Medical and Health Sciences, Jamshoro, from March 2003 to March 2004. PATIENTS AND METHODS The case records of all the gestational trophoblast...
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Gestational trophoblastic disease associated with ectopic pregnancy is a rare event and persistent trophoblastic disease is a well recognized complication of conservative surgical treatment for ectopic pregnancy but rarely secondary trophoblastic implantation may occur after salpingectomy. This is a case report of a rare and unusual presentation of persistent trophoblastic implantation followin...
متن کاملGestational trophoblastic disease: experience at Nawabshah Hospital.
BACKGROUND Gestational Trophoblastic Disease (GTD) is a heterogeneous group of diseases that includes partial and complete hydatidiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumour. The incidence of GTD varies in different parts of the world. The malignant potential of this disease is higher in South East Asia in comparison to western countries. Objectives of stu...
متن کاملپیشبینی ابتلا به نئوپلازی تروفوبلاستیک حاملگی با استفاده از داده های طولی هورمون گونادوتروپین جفتی انسان طی 21 روز پس از تخلیه مول
Background: Gestational Trophoblastic Neoplasia (GTN) is the malignant form of gestational trophoblastic disease that has different capabilities in metastasis and invasion stance. Therefore, the aim of this study was to identify an appropriate and applicable longitudinal marker, using the serum human chorionic gonadotropin (hCG) levels during 21 days after mole evacuation for predicting the ges...
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The efficacy of single-agent chemotherapy for patients with low risk gestational trophoblastic neoplasia (LRGTN) with methotrexate or dactinomycin is well established, but efforts continue to reduce the toxicity, the patients time and cost of treatment. In a randomized clinical trial, we evaluated and compared the efficacy, toxicity and cost effectiveness of pulse-methotrexate versus pulse-dact...
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ورودعنوان ژورنال:
- The Ceylon medical journal
دوره 50 3 شماره
صفحات -
تاریخ انتشار 2005